Daftar pemain Man of the Match Copa America Centenario jadi ajang penilaian siapa yang bakal terpilih jadi pemain terbaik dalam turnamen ini.
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- CRISTIAN ZAPATA/Kolombia (Man of the Match USA 0-2 Kolombia)
- GUSTAVO GOMEZ/Paraguay (Man of the Match Kosta Rika 0-0 Paraguay)
- JOSE PAOLO GUERRERO/Peru (Man of the Match Peru 1-0 Haiti)
- ESTEBAN DREER/Ekuador (Man of the Match Ekuador 0-0 Brasil)
- JOSEF MARTINEZ/Venezuela (Man of the Match Venezuela 1-0 Jamaika)
- RAFAEL MARQUEZ/Meksiko (Man of the Match Meksiko 3-1 Uruguay)
- BLAS PEREZ/Panama (Man of the Match Panama 2-1 Bolivia)
- ANGEL DI MARIA/Argentina (Man of the Match Argentina 2-1 Chile)
- JERMAINE JONES/USA (Man of the Match USA 4-0 Kosta Rika)
- JAMES RODRIGUEZ/Kolombia (Man of the Match Kolombia 2-1 Paraguay)
- PHILIPPE COUTINHO/Brasil (Man of the Match Brasil 7-1 Haiti)
- ENNER REMBERTO VALENCIA/Ekuador (Man of the Match Peru 2-2 Ekuador)
- SALOMON RONDON/Venezuela (Man of the Match Venezuela 1-0 Uruguay)
- JAVIER HERNANDEZ/Meksiko (Man of the Match Meksiko 2-0 Jamaika)
- ARTURO VIDAL/Chile (Man of the Match Chile 2-1 Bolivia)
- LIONEL MESSI/Argentina (Man of the Match Argentina 5-0 Panama)
- JOHN ANTHONY BROOKS/USA (Man of the Match USA 1-0 Paraguay)
- CELSO BORGES/Kosta Rika (Man of the Match Kolombia 2-3 Kosta Rika)
- ENNER REMBERTO VALENCIA/Ekuador (Man of the Match Ekuador 4-0 Haiti)
- PEDRO GALLESE/Peru (Man of the Match Peru 1-0 Brasil)
- JESUS CORONA/Meksiko (Man of the Match Meksiko 1-1 Venezuela)
- ABEL HERNANDEZ/Uruguay (Man of the Match Uruguay 3-0 Jamaika)